The Arginine, it is amino acid, is most popular in bodybuilding as supplement to improve the pump, this pump is made from increase the Nitric oxide NO and vascularisation, for this reasons present in most of pre-workout.
Principally synthesized in the liver and kindness, Arginine has involved in most of physiological functions like produce the Nitric oxide, production on Creatine, ammonia, urea and release the growth hormone (GH). The Arginine is precursor of Creatine, it increase the capacity to synthesis of Creatine and, for this reason, improve the strength.
The Arginine is involved in a lot of metabolic pathways like Urea and Creatine synthesis, but the most primary function is increase the Nitric Oxide levels. The Nitric Oxide helps to regulate the blood flow of skeletal muscles during the exercises thought release of endothelium dependent in the cardiovascular muscles (veins).
The benefits of Arginine are a lot, especially for heart and blood but also:
Dispose of Ammonia
Precursor of Creatine formation
Produce Nitric Oxide
Improve erectile function
Help the regeneration of the cells of the epidermis.
Other benefits of Arginine, clinical treatment, are:
Produce Nitric oxide and increase the vascularisation
Increase the secretion of Growth Hormone (GH)
Promotion and stimulation of protein synthesis
The real effect of Arginine supplementation
The best effect of Arginine is the production of Nitric Oxide but this production is great with injunction of Arginine, because when you taken the capsule or powder of Arginine, the presence of enzyme arginase reduce the absorption of it and degrade the Arginine in Ornithine and Urea, with high dose of Arginine is demonstrated that can cause diarrhea. In part, the pump effect that you have after Arginine supplementation happens because the Arginine has stronger stimulation of Insulin that increase the pump and vasodilatation, also the insulin is stimulate with carbohydrates and protein powders
How we saw allow the real effect of Arginine, I do not like suggest to buy Arginine to have a good pump during the workout, most of peoples but Arginine or pre-workout that include Arginine, it is only waste money because the Arginine absorption are limited.
Anyway, you can have great vasodilatation with Citrulline supplementations, it has great effect on production of Nitric Oxide. I will explain better on the ne xt article, the effect of Citrulline, for now to have a good "pump" the dose of citrulline is 8 gr on your pre workout.